4-[[6-Amino-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethylbenzonitrile-d8
Product Name |
4-[[6-Amino-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethylbenzonitrile-d8
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Product Code |
A00007788
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Chemical name |
4-[[6-Amino-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethylbenzonitrile-d8
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Synonyms |
4-[[6-Amino-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethylbenzonitrile-d8
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Impurity |
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CAS Number |
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Alternate CAS # |
Unlabelled: 939431-68-2
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Molecular form |
C₂₀H₈D₈N₆O
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Appearance |
Pale Yellow Powder
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Melting Point |
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Mol. Weight |
364.43
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Storage |
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Solubility |
DMSO
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Stability |
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Category |
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Boiling Point |
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Applications |
4-[[6-Amino-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethylbenzonitrile-d8 is an intermediate in the synthesis of Etravirine-d8 (E937003). Etravirine-d8 is a novel labelled HIV reverse transcriptase inhibitor useful in treatment of HIV infection.
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Dangerous Goods Info |
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References |
Scholler-Gyure, M., et al.: J. Clin. Pharmacol., 48, 322 (2008); Thakur, A., et al.: Eur. J. Med. Chem., 43, 471 (2008)
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Extra Notes |
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Documents (MSDS) |
No Data Available
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Keywords |
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